Saturday, February 5, 2011

a prospective epidemiological study - Medical pre-hospital management reduces mortality in severe blunt trauma


Introduction
Severe blunt trauma is a leading cause of premature death and handicap. However, the benefit for the patient of pre-hospital management by emergency physicians remains controversial because it may delay admission to hospital. This study aimed to compare the impact of medical pre-hospital management performed by SMUR (Service Mobile d'Urgences et de Reanimation) with non-medical pre-hospital management provided by Fire Brigades (non-SMUR) on 30-day mortality.

Methods
The FIRST (French Intensive care Recorded in Severe Trauma) study is a multicenter cohort study on consecutive patients with severe blunt trauma requiring admission to university hospital intensive care units within the first 72 hours. Initial clinical status, pre-hospital life-sustaining treatments and Injury Severity Scores (ISS) were recorded. The main endpoint was 30-day mortality.

Results
Among 2703 patients, 2513 received medical pre-hospital management from SMUR, and 190 received basic pre-hospital management provided by Fire Brigades. SMUR patients presented a poorer initial clinical status and higher ISS and were admitted to hospital after a longer delay than non-SMUR patients. The crude 30-day mortality rate was comparable for SMUR and non-SMUR patients (17% and 15% respectively; p = 0.61). After adjustment for initial clinical status and ISS, SMUR care significantly reduced the risk of 30-day mortality (OR: 0.55, 95% CI: 0.32-0.94, p = 0.03). Further adjustments for the delay to hospital admission only marginally affected these results.

Conclusions
This study suggests that SMUR management is associated with a significant reduction in 30-day mortality. The role of careful medical assessment and intensive pre-hospital life-sustaining treatments need to be assessed in further studies.


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